A REVIEW PAPER ON NANOPARTICLES FOR DRUG DELIVERY
The study of nanostructured drug delivery systems enables the development of novel platforms for the efficient transport and controlled release of drug molecules in the harsh microenvironment of diseased tissues of living systems, providing a broad range of functional nano-platforms for smart biotechnology and nano-medicine applications. Recent developments in smart nano carriers consisting of organic materials (including polymer micelles and vesicles, liposomes, dendrimers and hydrogels) and inorganic materials (including quantum dots, gold and mesoporous silica nanoparticles) are highlighted in this article. Despite the remarkable advances in recent synthetic methodologies, the behaviour of most nano carriers is linked to a range of undesirable side effects that decrease their efficient use in applications of biotechnology and nanomedicine. This highlights some important problems arising from the complex environment and multiform interactions within the specific biological media in the design and engineering of nano carrier systems for biotechnology applications.