A REVIEW PAPER ON NANOPARTICLE AND TARGETED SYSTEMS FOR THE CANCER TREATMENT

Abstract

This analysis examines recent work aimed at more focused cancer care, either through more precise anticancer agents or through distribution methods. Such fields include dissemination by avoiding the reticuloendothelial system, using the improved permeability and retention effect and tumor-specific targeting. There are summarized therapeutic options using antibody-targeted therapies. It also addresses the potential to cure cancer by targeting delivery via angiogenesis and introduces antiangiogenic drugs in clinical trials. Methods of distribution that use nanoparticles directly are also illustrated, for both degradable and non-degradable polymers. Current cancer treatment typically includes invasive procedures, including catheter application to allow chemotherapy, initial chemotherapy to minimize any cancer present, surgery to remove the tumor(s) if necessary, followed by further chemotherapy and radiation. The aim of chemotherapy and radiation is to destroy tumor cells because, due to their growth at a much faster pace than healthy cells, these cells are more vulnerable to the actions of these drugs and methods, at least in adults.