A REVIEW PAPER ON CANCER MANAGEMENT AND THERAPY THROUGH DESIGNER NANOMATERIAL

Abstract

The ability of nanotechnology is to circumvent many limitations of traditional therapeutic formulations. Important progress has actually been made in the application of engineered nanomaterials with high precision, sensitivity and efficacy for the treatment of cancer. Tailor-made nanomaterials functionalized with unique ligands can predictably target cancer cells and effectively deliver encapsulated payloads. In addition, by changing their structure, scale, morphology, and surface chemistry, nanomaterials can also be engineered for increased drug loading, enhanced half-life in the body, controlled release, and selective delivery. As smart drug delivery systems for cancer treatment, polymeric nanomaterials, metallic nanoparticles, carbon-based materials, liposomes, and dendrimers have been developed to date, demonstrating improved pharmacokinetic and pharmacodynamics profiles over traditional formulations because of their nanoscale size and specific physicochemical characteristics. The knowledge provided in the literature indicates that nanotechnology can provide cancer management and anticancer therapy platforms for the next decade.