Comparative In Vitro Antioxidant Studies Of Extract Of Gardenia Latifolia, Terminalia Tomentosa And Lagerstroemia Parviflora

  • Prabhakar Budholiya, et. al.

Abstract

The objectives of this study are to screen the phytochemicals and determine the antioxidant capacity
of the extract of leaves Gardenia latifolia, Terminalia tomentosa and Lagerstroemia parviflora. The
methanolic extract of leaves Gardenia latifolia, Terminalia tomentosa and Lagerstroemia parviflora
were studied for antioxidant activity on different in vitro models namely 1,1-diphenyl, 2-picryl
hydrazyl (DPPH) assay and Nitric oxide radical scavenging method. Ascorbic acid used as standards
was also evaluated for comparison. The extracts showed dose dependent free radical scavenging
property in the tested models. The DPPH scavenging activity of methanolic extract of Gardenia
latifolia, Terminalia tomentosa, Lagerstroemia parviflora were showed percent inhibition
56.80µg/ml, 61.53µg/ml and 66.84µg/ml at different concentration of 10µg/ml, 20µg/ml, 40 µg/ml,
60µg/ml, 80µg/ml as compared to positive control ascorbic acid 21.41µg/ml. The NO scavenging
activity of methanolic extract of Gardenia latifolia, Terminalia tomentosa and Lagerstroemia
parviflora were 84.49µg/ml, 60.5549µg/ml and 66.1249µg/ml at different concentration of 10µg/ml,
20µg/ml, 40µg/ml, 60 µg/ml, 80 µg/ml, 100 µg/ml respectively. This activity was lower than ascorbic
acid, reference standard ascorbic acid showed IC50 29.01749µg/ml. The present study describes the
antioxidant activity of L. parviflora which will further used for medicinal applications.

Published
2019-12-15